In the alcoholic liver cirrhosis group, the CTP score C was significantly more common among the patients who died than in those who survived (87.5 vs. 152.15 ± 293.09 p = 0.997).ĭuring the follow-up period, 24/87 (27.6%) patients died in the alcoholic cirrhosis group versus 13/39 (33.3%) in the nonalcoholic group the difference was not statistically significant ( p = 0.658). There was no significant difference between the groups in serum sodium level (135.52 ± 3.75 mmol/L vs. The serum bilirubin was also significantly higher in the alcoholic cirrhosis group than in the nonalcoholic cirrhosis group (106.98 ± 133.28 µmol/L vs. Among the biochemical parameters (Table 1), the mean serum GGT value was significantly higher in the alcoholic cirrhosis group than in the nonalcoholic cirrhosis group (317.24 ± 478.05 U/L vs. The median follow-up period was 6.5 months (range: 1-29) in the alcoholic group and 6.5 months (range: 1-26) in the nonalcoholic group. The mean age was comparable between the groups: 54.46 ± 10.3 years for alcoholic cirrhosis patients and 59.71 ± 11.56 years for nonalcoholic cirrhosis patients. The authors concluded that those patients who do not improve their condition despite abstinence are the ones for whom transplantation is indicated. found that patients who continued to drink alcohol after hospital treatment for advanced liver cirrhosis died within 6-10 months. This shows preserved functional reserve of the liver, and these patients have significantly longer survival. Abstinence can significantly change the prognosis in the patient it leads to stabilization of the patient's condition and results in lowering the CTP score to A, which is not an indication for liver transplantation. emphasized the importance of achieving abstinence from alcohol. In terms of the optimal timing for liver transplantation in patients with alcoholic cirrhosis, Veldt et al. It is also very important to honor the ethical, moral, and religious values of society. Organ and tissue transplantation is successful only if everyone involved in the process, including physicians and medical institutions, respect and consider the best interests of the patients. Results: The updated MELD score had the highest predictive value (3.29) among the tested scores (95% CI: 2.26-4.78). Their discriminatory ability was evaluated using receiver operating characteristic (ROC) curve analysis. Cox regression analysis was used to assess the ability of each of the scores for predicting mortality in patients with alcoholic cirrhosis. For each patient, prognostic scores were calculated these included the Child-Turcotte-Pugh score (CTP score), CTP creatinine-modified I score, CTP creatinine-modified II score, Model for End-Stage Liver Disease (MELD score), MELD model for end-stage liver disease sodium-modified score, Integrated MELD score, updated MELD score, United Kingdom MELD, and the MELD score remodeled by serum sodium index (MESO index). Material and Methods: In this prospective study, 126 patients were enrolled and followed up for 29 months. Objective: To identify the prognostic score that is the best predictor of outcome in patients hospitalized with decompensated liver cirrhosis.
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